Joe Manganiello Reveals Autoimmune Illness Led to Sofía Vergara Divorce

Actor Joe Manganiello details his seven-year autoimmune battle and its impact on marriage to Sofía Vergara in new memoir.

Editorial Desk

October 8, 2026 One Min Read

POLICY WIRE — New York, United States — Actor Joe Manganiello has revealed the severe health struggles that led to his divorce from Sofía Vergara, as detailed in his upcoming memoir, ‘Bloodlines.’

Manganiello, 49, described a seven-year ordeal with an autoimmune illness that left him fearing for his life. The condition caused significant physical and emotional strain, leading to multiple surgeries and a weight loss of 60 pounds between 2015 and 2022.

📄 POLICY WIRE WHITEPAPER PUBLISHED: PAKISTAN’S NATIONAL SECURITY POLICY PRIORITIES

👉 READ BY CLICKING HERE

The actor shared how the illness affected his relationship with Vergara, whom he married in 2015 and divorced in 2023. He spoke about the emotional distance that developed, including claims that she refused to hug him. The couple also faced challenges over having children, with Manganiello expressing concerns about leaving her with a child not biologically his.

Reporting by Policy-Wire (PW)

Author

Editorial Desk

Policy Wire is your go-to editorial hub for insightful perspectives and informed analysis on pressing policy issues, both regionally and globally. Over the years, Policy Wire has collaborated with leading international news agencies—including AFP, AP, Reuters, and others—to provide fact-based reporting and nuanced commentary. With a commitment to clarity and credibility, we aim to bridge the gap between complex policy debates and public understanding, ensuring that our readers stay informed on the issues shaping the world today.