Gen Z Women Report Highest Levels of Chronic Fatigue, CDC Study Reveals

CDC study shows Gen Z women most affected by chronic fatigue, linked to mental health and lifestyle factors.

September 17, 2026 One Min Read

POLICY WIRE — Washington, D.C. — A recent federal analysis reveals that nearly three-quarters of U.S. adults experience frequent fatigue, with Gen Z women reporting the highest levels, according to the Centers for Disease Control and Prevention.

The study, based on data from 27,000 adults, found that over 16 percent reported feeling exhausted or very tired on most days or every day. The CDC highlighted that Gen Z and millennial adults were more likely to report these symptoms compared to other age groups.

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Women were disproportionately affected, with 20 percent reporting persistent fatigue versus 13 percent of men. The highest prevalence was among women aged 18–34. The findings also showed a strong link between frequent fatigue and mental health challenges, including depression and anxiety, which affect nearly 44 million American adults.

Reporting by Policy-Wire (PW)

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